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科学研究

序号	论文名称	通讯作者	发表刊物及年度、页数等	刊物级别
1	Synthesis, in vitro and in vivo biological	全哲山	Acta Pharmaceutica Sinica B, 2020,10（4）：628-645）	SCI 1区
2	P2X7 receptor-targeted regulation by tetrahydroxystilbene glucoside in alcoholic hepatosteatosis: A new strategy towards	南极星	British Journal of Pharmacology，2020, DOI: 10.1111/bph.15007	SCI 1区
3	Signaling pathways involved in p38-ERK and inflammatory factors mediated the anti-fibrosis effect of AD-2 on thioacetamide-induced liver injury in mice	吴艳玲	Food Funct. 2019，10(7):3992-4000	SCI 1区
4	Synthesis, and evaluation of in vitro and in vivo anticancer activity of 14-substituted oridonin analogs: A novel and potent cell cycle arrest and apoptosis inducer through the p53-MDM2 pathway cell cycle arrest and apoptosis inducer through the p53-MDM2 pathway.	全哲山	Eur J Med Chem, 2019, 173, 15-31	SCI 1区
5	Synthesis and Biological Evaluation of (+)-Usnic Acid Derivatives as Potential Anti-Toxoplasma gondii Agents.	全哲山	J Agric Food Chem. 2019,67(34): 9630-9642	SCI 1区
6	Design, synthesis, and antifibrosis evaluation of 4-(benzo-[c][1,2,5]	金成华	Eur J Med Chem, 2019, 180: 15-27.	SCI 1区
7	Synthesis and biological evaluation of tryptophan-derived rhodanine derivatives as PTP1B inhibitors and anti-bacterial agents	孙良鹏	Eur J Med Chem, 2019, 172: 163-173	SCI 1区
8	Panaxadiol inhibits programmed cell death-ligand 1 expression and tumour	金学军	Pharmacol Res. 2020，155:104727	SCI 2区
9	Thymoquinone Attenuates Acetaminophen Overdose-Induced Acute Liver Injury and Inflammation Via Regulation of JNK and AMPK Signaling Pathway	南极星	Am J Chin Med. 2019;47(3):577-594.	SCI 2区
10	Acanthoic acid modulates lipogenesis in nonalcoholic fatty liver disease via FXR/LXRs-dependent manner.	吴艳玲	Chem Biol Interact. 2019 ，311:108794	SCI 2区
11	Convallatoxin protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-κB signaling through activation of PPARγ.	金学军	Pharmacol Res. 2019 ，147:104355	SCI 2区
12	Liver kinase B1/AMP-activated protein kinase-mediated regulation by gentiopicroside ameliorates P2X7 receptor-dependent	南极星	British Journal of Pharmacology，2018,175:1451-70	SCI 1区
13	Amelioration of Alcoholic Liver Steatosis by Dihydroquercetin through the Modulation of AMPK-Dependent Lipogenesis Mediated by P2X7R−NLRP3-Inflammasome Activation	南极星	J. Agric. Food Chem，2018,48:4862-71	SCI 1区
14	Ginsenoside 25-OCH 3 ‑PPD Promotes Activity of LXRs To Ameliorate P2X7R-Mediated NLRP3 Inflammasome in the Development of Hepatic Fibrosis	南极星	J. Agric. Food Chem，2018,66:7023-35	SCI 1区
15	Synthesis and evaluation of novel arctigenin derivatives as potential anti-Toxoplasma gondii agents	全哲山	Eur J Med Chem, 2018,158:414-27	SCI 1区
16	Zinc finger protein 91 positively regulates the production of IL-1 beta in macrophages by activation of MAPKs and non-canonical caspase-8 inflammasome	金学军	BRITISH JOURNAL OF PHARMACOLOGY，2018，175： 4338-435	SCI 1区
17	Synergistic Inhibitory Effects of Acacetin and 11 Other Flavonoids Isolated from Artemisia sacrorum on Lipid Accumulation in 3T3-L1 Cells	朴光春	J. Agric. Food Chem，2018,66:12931-940	SCI 1区
18	Inhibition of P2x7R-NLRP3 inflammasome activation by Pleurotus citrinopileatus: a possible protective role in alcoholic hepatosteatosis	南极星	J. Agric. Food Chem，2018,66:13183-190	SCI 1区
19	Fraxinellone has anticancer activity in vivo by inhibiting programmed cell death-ligand 1 expression by reducing hypoxia-inducible factor-1α and STAT3	马娟	pharmacological research，2018,135:166-180	SCI 2区
20	A novel, simplified strategy of relative quantification N-glycan: Quantitative glycomics using electrospray ionization mass spectrometry through the stable isotopic labeling by transglycosylation reaction of mutant enzyme Endo-M-N175Q	闵俊哲	Journal of Pharmaceutical and Biomedical Analysis 149 (2018) 365–373	SCI 2区
21	Determination of D,L-Amino Acids in Collagen from Pig and Cod Skins by UPLC Using Pre-column Fluorescent Derivatization	闵俊哲	Food Analytical Methods,2018,11:3130-3137	SCI 2区
22	Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways	金学军	J Ethnopharmacol. 2017 May 5;203:27-38	SCI 2区
23	Synthesis and evaluation of a novel chiral derivatization reagent for resolution of carboxylic acid enantiomers by RP-HPLC	闵俊哲	Microchemical Journal, 2017, 135, 213-220	SCI 2区
24	Acanthoic acid protectsagainst ethanol-induced liver injury: Possible role of AMPK activation and IRAK4 inhibition.	南极星	Toxicol Lett. 2017，281:127-138.	SCI 2区
25	Acanthoic Acid Can Partially Prevent Alcohol Exposure-Induced Liver Lipid Deposition and Inflammation.	南极星	Front Pharmacol. 2017， 16;8:134.	SCI 2区
26	Potentiation of hepatic stellate cell activation by extracellular ATP is dependent on P2X7R-mediated NLRP3 inflammasome activation	廉丽花	Pharmacol Res. 2017,117:82-93	SCI 2区
27	Highly sensitive derivatization reagents possessing positively chargedstructures for the determination of oligosaccharides in glycoproteinsby high-performance liquid chromatography electrospray ionizationtandem mass spectrometry	闵俊哲	Journal of Chromatography A, 2016，1465：79-89	SCI2区
28	Upregulation of SIRT1-AMPK by thymoquinone in hepatic stellate cells ameliorates liver injury	南极星	Toxicol Lett. 2016， 16;262:80-91	SCI2区
29	Cucurbitacin E ameliorates hepatic fibrosis in vivo and in vitro through activation of AMPK and blocking mTOR-dependent signaling pathway	南极星	Toxicol Lett. 2016，258:147-58.	SCI2区
30	Betulin alleviated ethanol-induced alcoholic liver injury via SIRT1/AMPK signaling pathway.	南极星	Pharmacol Res. 2016，105:1-12.	SCI2区

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科学研究